2024

R Maddamsetti, ML Wilson, HI Son, Z Zhou, J Lu, L You. Scaling laws of plasmids across the microbial tree of life bioRxiv

HR Ma, HZ Xu, K Kim, DJ Anderson, L You. Private benefit of β-lactamase dictates selection dynamics of combination antibiotic treatment. Nature Communications

J Lu, N Luo, S Liu, K Sahu, R Maddamsetti, Y Baig, L You. Decoding pattern formation rules by integrating mechanistic modeling and deep learning bioRxiv

Y Dai, Z Zhou, W Yu, Y Ma, K Kim, N Rivera, J Mohammed, E Lantelme, A Chilkoti, L You Biomolecular condensates regulate cellular electrochemical equilibria. Cell

E Simsek, K Kim, J Lu, A Silver, N Luo, C T Lee, L You A ‘rich-get-richer’mechanism drives patchy dynamics and resistance evolution in antibiotic-treated bacteria Molecular Systems Biology

Y Ha, H R Ma, F Wu, A Weiss, K Duncker, H Z Xu, J Lu, M Golovsky, D Reker, L You Data-driven learning of structure augments quantitative prediction of biological responses PLOS Computational Biology

N Luo, J Lu, E Şimşek, A Silver, Y Yao, X Ouyang, S A West, L You The collapse of cooperation during range expansion of Pseudomonas aeruginosa Nature microbiology

T Wang, A Weiss, L You A generic approach to infer community-level fitness of microbial genes PNAS

G S Hamrick, R Maddamsetti, H Son, M L Wilson, H M Davis, L You Programming dynamic division of labor using horizontal gene transfer ACS Synthetic Biology

Z Li, Q Shen, E T Usher, A P Anderson, M Iburg, R Lin, B Zimmer, M D Meyer, A S Holehouse, L You, A Chilkoti, Y Dai, G J Lu Phase transition of GvpU regulates gas vesicle clustering in bacteria Nature microbiology

K Kim, A Weiss, H R Ma, H Son, Z Zhou, L You Antibiotic-mediated microbial community restructuring is dictated by variability in antibiotic susceptibility and population interactions bioRxiv

Y Dai, R Zare, L You, A Chilkoti Lightning the Interface: the Electrochemical Features of Biomolecular Condensates Bulletin of the American Physical Society

R Maddamsetti, Y Yao, T Wang, J Gao, V T Huang, G S Hamrick, H Son, L You Duplicated antibiotic resistance genes reveal ongoing selection and horizontal gene transfer in bacteria Nature Communications

A M Duda, H R Ma, C A Villalobos, S A Kuhn, K He, S R Seay, A C Jackson, C M Suh, E A Puccio, D A Anderson, V G Fowler Jr, L You, K J Franz An engineered prodrug selectively suppresses β-lactam resistant bacteria in a mixed microbial setting bioRxiv

R Maddamsetti, L You Circular RNA Obelisk-Ss is highly abundant in Streptococcus sanguinis SK36 bioRxiv

2023

Y Baig, H R Ma, H Xu, L You Autoencoder neural networks enable low dimensional structure analyses of microbial growth dynamics Nature Communications

A Weiss, T Wang, L You Promotion of plasmid maintenance by heterogeneous partitioning of microbial communities Cell systems

Y Dai, C Chamberlayne, M Messina, C Chang, R Zare, L You, A Chilkoti. Interaction of Biomolecular Condensates Influences Redox Reactions. Chem

K Kim, T Wang, HR Ma, E Şimşek, B Li, V Andreani, L You (2023). Mapping single-cell responses to population-level dynamics during antibiotic treatment. Molecular Systems Biology

Y Dai, M Farag, D Lee, X Zeng, K Kim, H Son, X Guo, J Su, N Peterson, J Mohammed, M Ney, D M Shapiro, R V Pappu, A Chilkoti, L You Programmable synthetic biomolecular condensates for cellular control Nature Chemical Biology

Y Dai, L You, A Chilkoti (2023) Engineering synthetic biomolecular condensates Nature Reviews Bioengineering

A Silver, L You, (2023). A change of phase. Nature Chemical Biology

J Luo, J Chen, Y Huang, L You, Z Dai (2023). Engineering living materials by synthetic biology. Biophysics Reviews

JH Bethke, HR Ma, R Tsoi, L Cheng, M Xiao, L You Vertical and horizontal gene transfer tradeoffs direct plasmid fitness Molecular Systems Biology

Z Li, Q Shen, Y Dai, AP Anderson, M Iburg, R Lin, B Zimmer, MD Meyer, L You., A Chilkoti, G Lu. (2023) Spatial Organization of Gas Vesicles is Governed by Phase-separable GvpU bioRxiv

2022

E Şimşek, Y Yao, D Lee, L You(2022). Toward predictive engineering of gene circuits. Trends in Biotechnology.

T Wang, L You (2022). Bringing cells to the edge. eLife

T Wang, A Weiss, A Aqeel, F Wu, AJ Lopatkin, LA David, L You Horizontal gene transfer enables programmable gene stability in synthetic microbiota Nature chemical biology

J Lu, R Tsoi, N Luo, Y Ha, S Wang, M Kwak, Y Baig, N Moiseyev, S Tian, A Zhang, NZ Gong, L You(2022) Distributed information encoding and decoding using self-organized spatial patterns Patterns

CA Roden, Y Dai, CA Giannetti, I Seim, M Lee, R Sealfon, GA McLaughlin, MA Boerneke, C Iserman, SA Wey, JL Ekena, OG Troyanskaya, KM Weeks, L You, A Chilkoti, AS Gladfelter Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures Nucleic acids research

L Wang, X Zhang, C Tang, P Li, R Zhu, J Sun, Y Zhang, H Cui, J Ma, X Song, W Zhang, X Gao, X Luo, L You, Y Chen, Z Dai Engineering consortia by polymeric microbial swarmbots Nature Communications

J Lu, E Şimşek, A Silver, L You Advances and challenges in programming pattern formation using living cells Current opinion in chemical biology

Y Yao, R Maddamsetti, A Weiss, Y Ha, T Wang, S Wang, L You Intra-and interpopulation transposition of mobile genetic elements driven by antibiotic selection Nature Ecology & Evolution

F Wu, Y Ha, A Weiss, M Wang, J Letourneau, S Wang, N Luo, S Huang, CT Lee, LA David, L You Modulation of microbial community dynamics by spatial partitioning Nature chemical biology

B Chen, W Kang, J Sun, R Zhu, Y Yu, A Xia, M Yu, M Wang, J Han, Y Chen, LT, Q Tian, Y Yu, G Li, L You, Z Liu, Z Dai Programmable living assembly of materials by bacterial adhesion Nature chemical biology

J Gore, L You Editorial overview: All microbial systems go. Current Opinion in Microbiology

G Jin, S Hong, J Rich, J Xia, K Kim, L You, C Zhao, TJ Huang Intelligent nanoscope for rapid nanomaterial identification and classification Lab on a Chip

2021

KE Duncker, ZA Holmes, L You Engineered microbial consortia: strategies and applications Microbial Cell Factories

T Wang, A Weiss, Y Ha, L You Predicting plasmid persistence in microbial communities by coarse‐grained modeling BioEssays

HI Son, A Weiss, L You Design patterns for engineering genetic stability Current opinion in biomedical engineering

V Andreani, L You, P Glaser, G Batt A model-based approach to characterize enzyme-mediated response to antibiotic treatments: going beyond the SIR classification bioRxiv

Z Dai, X Yang, F Wu, L Wang, K Xiang, P Li, Q Lv, J Tang, A Dohlman, L Dai, X Shen, L You (2021) Living fabrication of functional semi-interpenetrating polymeric materials Nature Communications

N Luo, S Wang, J Lu, X Ouyang, L You Collective colony growth is optimized by branching pattern formation in Pseudomonas aeruginosa Molecular systems biology

Y Cao, J Neu, AE Blanchard, T Lu, L You Repulsive expansion dynamics in colony growth and gene expression PLoS computational biology

2020

T Wang, L You The persistence potential of transferable plasmids Nature communications

C Zhang, W Song, HR Ma, X Peng, DJ Anderson, VG Fowler Jr, ... Temporal encoding of bacterial identity and traits in growth dynamics Proceedings of the National Academy of Sciences

MM Villa, RJ Bloom, JD Silverman, HK Durand, S Jiang, A Wu, EP Dallow, S Huang, L You, LA David Interindividual variation in dietary carbohydrate metabolism by gut bacteria revealed with droplet microfluidic culture Msystems

K Kim, L You Bacterial Aggregation Leads to Collective Elimination Trends in microbiology

B Mathey-Prevot, BT Parker, C Im, C Hong, P Dong, G Yao, L You Quantifying E2F1 protein dynamics in single cells Quantitative Biology

JH Bethke, A Davidovich, L Cheng, AJ Lopatkin, W Song, JT Thaden, VG Fowler Jr, ,M Xiao, L You Environmental and genetic determinants of plasmid mobility in pathogenic Escherichia coli Science advances

2019

K Zhu, S Chen, TA Sysoeva, L You Universal antibiotic tolerance arising from antibiotic-triggered accumulation of pyocyanin in Pseudomonas aeruginosa PLoS biology

AJ Lopatkin, JM Stokes, EJ Zheng, JH Yang, MK Takahashi, L You, JJ Collins Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate Nature microbiology

R Tsoi, Z Dai, L You Emerging strategies for engineering microbial communities Biotechnology advances

Z Dai, AJ Lee, S Roberts, TA Sysoeva, S Huang, M Dzuricky, X Yang, X Zhang, Z Liu, A Chilkoti, L You Versatile biomanufacturing through stimulus-responsive cell–material feedback Nature Chemical Biology

S Wang, K Fan, N Luo, Y Cao, F Wu, C Zhang, KA Heller, L You Massive computational acceleration by using neural networks to emulate mechanism-based biological models Nature communications

HR Ma, L You Polar-opposite fates Nature Chemical Biology

JR Simon, SA Eghtesadi, M Dzuricky, L You, A Chilkoti Engineered ribonucleoprotein granules inhibit translation in protocells Molecular cell

W Song, HX Sun, C Zhang, L Cheng, Y Peng, Z Deng, D Wang, Y Wang, M Hu, W Liu, H Yang, Y Shen, Junhua Li, L You, M Xiao Prophage Hunter: an integrative hunting tool for active prophages Nucleic Acids Research

N Luo, S Wang, L You Synthetic pattern formation Biochemistry

F Wu, AJ Lopatkin, DA Needs, CT Lee, S Mukherjee, L You A unifying framework for interpreting and predicting mutualistic systems Nature communications

TA Sysoeva, YL Kim, J Rodriguez, AJ Lopatkin, L You Growth‐Stage‐Dependent Regulation of Conjugation AIChE Journal

2018

HR Meredith, V Andreani, HR Ma, AJ Lopatkin, AJ Lee, DJ Anderson, G Batt, L You Applying ecological resistance and resilience to dissect bacterial antibiotic responses Science advances

P Dong, MV Maddali, JK Srimani, F Thelot, JR Nevins, B Mathey-Prevot, L You Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control NATURE COMMUNICATIONS

Y Feng, KE Marusak, L You, S Zauscher Biosynthetic transition metal chalcogenide semiconductor nanoparticles: progress in synthesis, property control and applications Current Opinion in Colloid & Interface Science

H Park, S Huang, KA Walzer, L You, JTA Chi, NE Buchler Heterogeneous timing of asexual cycles in Plasmodium falciparum quantified by extended time-lapse microscopy bioRxiv

L You, E Takano Synthetic Biology: Reports from CSHA 2016 and More Biotechnology

AJ Lee, S Wang, HR Meredith, B Zhuang, Z Dai, L You Robust, linear correlations between growth rates and β-lactam–mediated lysis rates Proceedings of the National Academy of Sciences

TA Sysoeva, Y Kim, L You REGULATION OF CONJUGATIVE TRANSFER OF β-LACTAM RESISTANCE FROM UROPATHOGENIC STRAINS OF ESCHERICHIA COLI The Journal of Urology

R Tsoi, F Wu, C Zhang, S Bewick, D Karig, L You Metabolic division of labor in microbial systems Proceedings of the National Academy of Sciences

KE Marusak, JR Krug, Y Feng, Y Cao, L You, S Zauscher Bacterially driven cadmium sulfide precipitation on porous membranes: Toward platforms for photocatalytic applications Biointerphases

P Dong, C Zhang, BT Parker, L You, B Mathey-Prevot 8 Cyclin D/CDK4/6 activity controls G1 length in mammalian cells PloS one

2017

F Wu, JH Bethke, M Wang, L You Quantitative and synthetic biology approaches to combat bacterial pathogens Current opinion in biomedical engineering

AJ Lopatkin, HR Meredith, JK Srimani, C Pfeiffer, R Durrett, L You Persistence and reversal of plasmid-mediated antibiotic resistance Nature communications

Y Cao, Y Feng, MD Ryser, K Zhu, G Herschlag, C Cao, K Marusak, S Zauscher, L You Programmable assembly of pressure sensors using pattern-forming bacteria Nature biotechnology

JK Srimani, S Huang, AJ Lopatkin, L You Drug detoxification dynamics explain the postantibiotic effect

Molecular Systems Biology

F Wu, L You Hacking DNA copy number for circuit engineering Nature Genetics

L You Programming Bacteria in Time and Space. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Y Tanouchi, A Pai, H Park, S Huang, NE Buchler, L You Long-term growth data of Escherichia coli at a single-cell level Scientific data

Y Feng, E Ngaboyamahina, KE Marusak, Y Cao, L You, JT Glass, S Zauscher Hybrid (organic/inorganic) electrodes from bacterially precipitated CdS for PEC/storage applications The Journal of Physical Chemistry

I Shats, M Deng, A Davidovich, C Zhang, JS Kwon, D Manandhar, R Gordân, G Yao, L You. Expression level is a key determinant of E2F1-mediated cell fate Cell Death & Differentiation

2016

Y Cao, A Lopatkin, L You Elements of biological oscillations in time and space Nature Structural & Molecular Biology

AJ Lopatkin, TA Sysoeva, L You Dissecting the effects of antibiotics on horizontal gene transfer: Analysis suggests a critical role of selection dynamics Bioessays

C Zhang, R Tsoi, F Wu, L You Processing oscillatory signals by incoherent feedforward loops PLoS computational biology

Y Cao, MD Ryser, S Payne, B Li, CV Rao, L You Collective space-sensing coordinates pattern scaling in engineered bacteria Cell

C Zhang, R Tsoi, L You Addressing biological uncertainties in engineering gene circuits Integrative biology

AJ Lopatkin, S Huang, RP Smith, JK Srimani, TA Sysoeva, S Bewick, D Karig, L You Antibiotics as a selective driver for conjugation dynamics Nature microbiology

S Huang, AJ Lee, R Tsoi, F Wu, Y Zhang, KW Leong, L You, Coupling Spatial Segregation with Synthetic Circuits to Control Bacterial Survival Molecular Systems Biology

KE Marusak, Y Feng, CF Eben, ST Payne, Y Cao, L You, S Zauscher Cadmium sulphide quantum dots with tunable electronic properties by bacterial precipitation RSC advances

2015

S Huang, JK Srimani, AJ Lee, Y Zhang, AJ Lopatkin, KW Leong, L You Dynamic control and quantification of bacterial population dynamics in droplets Biomaterials

Y Tanouchi, A Pai, H Park, S Huang, R Stamatov, NE Buchler, L You A noisy linear map underlies oscillations in cell size and gene expression in bacteria Nature

TJ Lee, J Wong, S Bae, AJ Lee, A Lopatkin, F Yuan, L You A power-law dependence of bacterial invasion on mammalian host receptors PLoS computational biology

HR Meredith, AJ Lopatkin, DJ Anderson, L You Bacterial Temporal Dynamics Enable Optimal Design of Antibiotic Treatment PLoS computational biology

HR Meredith, JK Srimani, AJ Lee, AJ Lopatkin, L You Collective antibiotic tolerance: mechanisms, dynamics and intervention Nature Chemical Biology

RP Smith, L Boudreau, L You Engineering cell-to-cell communication to explore fundamental questions in ecology and evolution The physical basis of bacterial quorum communication

2014

JK Srimani, L You Emergent dynamics from quorum eavesdropping Chemistry & biology

D Eidum, K Asthana, S Unni, M Deng, L You Construction, visualization, and analysis of biological network models in Dynetica Quantitative Biology

AJ Lopatkin, L You Synthetic Biology Looks Good on Paper Cell

B Li, L You Stochastic sensitivity analysis and kernel inference via distributional data Biophysical journal

P Dong, MV Maddali, JK Srimani, F Thélot, JR Nevins, B Mathey-Prevot, L You Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control Nature communications

JK Srimani, G Yao, J Neu, Y Tanouchi, TJ Lee, L You Linear population allocation by bistable switches in response to transient stimulation PLoS One

C Tan, RP Smith, MC Tsai, R Schwartz, L You Phenotypic signatures arising from unbalanced bacterial growth PLoS computational biology

A Pai, JK Srimani, Y Tanouchi, L You Generic metric to quantify quorum sensing activation dynamics ACS synthetic biology

L You Engineering bacteria to cooperate, sacrifice, and organize Advances in Systems and Synthetic Biology

AJ Lee, L You Cells Listen to Their Inner Voice Science

R Smith, C Tan, JK Srimani, A Pai, KA Riccione, H Song, L You Programmed Allee effect in bacteria causes a tradeoff between population spread and survival Proceedings of the National Academy of Sciences

S Payne, L You Engineered cell–cell communication and its applications Productive biofilms

2013

I Shats, ML Gatza, B Liu, SP Angus, L You, JR Nevins FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function Cancer research

Y Tanouchi, AJ Lee, H Meredith, L You Programmed cell death in bacteria and implications for antibiotic therapy Trends in microbiology

B Li, L You Predictive power of cell-to-cell variability Quantitative Biology

Y Zhang, YP Ho, YL Chiu, HF Chan, B Chlebina, T Schuhmann, L You, KW Leong A programmable microenvironment for cellular studies via microfluidics-generated double emulsions Biomaterials

RP Smith, Y Tanouchi, L You Synthetic microbial consortia and their applications Synthetic biology

T Lee, G Yao, L You Cell Cycle Transition, Principles of Restriction Point Encyclopedia of Systems Biology

S Payne, B Li, Y Cao, D Schaeffer, MD Ryser, L You Temporal control of self‐organized pattern formation without morphogen gradients in bacteria Molecular systems biology

RP Smith, Y Tanouchi, L You Synthetic microbial consortia and their applications Synthetic biology

2012

A Pai, Y Tanouchi, L You Optimality and robustness in quorum sensing (QS)-mediated regulation of a costly public good enzyme Proceedings of the National Academy of Sciences

Y Tanouchi, A Pai, NE Buchler, L You Programming stress-induced altruistic death in engineered bacteria Molecular Systems Biology

C Tan, RP Smith, JK Srimani, KA Riccione, S Prasada, M Kuehn, L You The inoculum effect and band-pass bacterial response to periodic antibiotic treatment Molecular Systems Biology

Y Tanouchi, RP Smith, L You Engineering microbial systems to explore ecological and evolutionary dynamics Current opinion in biotechnology

JW Chin, L You A different life? Current Opinion in Chemical Biology

JE Stone, PN Benfey, L You Promoting Collaborative Interdisciplinary Research at the Duke Center for Systems Biology ACS Synthetic Biology

JV Wong, B Li, L You Tension and robustness in multitasking cellular networks PLoS computational biology

L You Coping with stress in a synthetic world APS March Meeting Abstracts

Y Tanouchi, RP Smith, L You Engineered gene circuits that program population dynamics: a review Current Opinion in Biotechnology

H Song, L You Modeling spatiotemporal dynamics of bacterial populations Computational Modeling of Signaling Networks

S Payne, RP Smith, L You Quantitative analysis of the spatiotemporal dynamics of a synthetic predator–prey ecosystem Synthetic Gene Networks: Methods and Protocols

2011

M Hallen, B Li, Y Tanouchi, C Tan, M West, L You Computation of Steady-State Probability Distributions in Stochastic Models of Cellular Networks PLoS Computational Biology

JV Wong, P Dong, JR Nevins, B Mathey-Prevot, L You Network calisthenics: control of E2F dynamics in cell cycle entry Cell Cycle

H Song, S Payne, C Tan, L You Programming microbial population dynamics by engineered cell–cell communication Biotechnology journal

N Elliott, T Lee, L You, F Yuan Proliferation behavior of E. coli in a three-dimensional in vitro tumor model Integrative biology

G Yao, C Tan, M West, JR Nevins, L You Origin of bistability underlying mammalian cell cycle entry Molecular systems biology

JV Wong, G Yao, JR Nevins, L You Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC Molecular cell

B Li, L You Synthetic biology: Division of logic labour Nature

JV Wong, G Yao, JR Nevins, L You Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells Methods in Enzymology

FV Bonassi, L You, M West Bayesian learning from marginal data in bionetwork models Statistical Applications in Genetics and Molecular Biology

2010

TJ Lee, G Yao, DC Bennett, JR Nevins, L You Stochastic E2F activation and reconciliation of phenomenological cell-cycle models PLoS Biology

P Marguet, Y Tanouchi, E Spitz, C Smith, L You Oscillations by minimal bacterial suicide circuits reveal hidden facets of host-circuit physiology PloS one

RP Smith, L You Engineering microbial consortia and applications of synthetic ecosystems

Q Wang, J Niemi, CM Tan, L You, M West Image segmentation and dynamic lineage analysis in single‐cell fluorescence microscopy Cytometry Part A: The Journal of the International Society for Advancement of Cytometry

H Song, S Payne, M Gray, L You Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem Nature chemical biology

2009

C Tan, P Marguet, L You Emergent bistability by a growth-modulating positive feedback circuit Nature chemical biology

A Pai, Y Tanouchi, CH Collins, L You Engineering multicellular systems by cell-cell communication Current opinion in biotechnology

A Pai, L You Optimal tuning of bacterial sensing potential Molecular systems biology

Y Tanouchi, A Pai, L You Decoding biological principles using gene circuits Mol. BioSyst

FJ Isaacs, L You A brave new synthetic world Genome biology

K Brenner, L You, FH Arnold Response to Goldman and Brown: Making sense of microbial consortia using ecology and evolution Biol. Sci

2008

C Smith, H Song, L You Signal discrimination by differential regulation of protein stability in quorum sensing Journal of molecular biology

K Brenner, L You, FH Arnold Engineering microbial consortia: a new frontier in synthetic biology Trends in Biotechnology

Y Tanouchi, D Tu, J Kim, L You Noise reduction by diffusional dissipation in a minimal quorum sensing motif PLoS computational biology

FK Balagaddé, H Song, J Ozaki, CH Collins, M Barnet, FH Arnold, ... A synthetic Escherichia coli predator–prey ecosystem Molecular systems biology

G Yao, TJ Lee, S Mori, JR Nevins, L You A bistable Rb–E2F switch underlies the restriction point Nature cell biology

T Lee, G Yao, J Nevins, L You Sensing and integration of Erk and PI3K signals by Myc PLoS computational biology

JV Wong, H Song, L You A whole more than the sum of its synthetic parts ACS Chemical Biology

2007

C Tan, F Reza, L You Noise-limited frequency signal transmission in gene circuits Biophysical journal

P Marguet, F Balagadde, C Tan, L You Biology by design: reduction and synthesis of cellular components and behaviour Journal of the Royal Society Interface

L You Engineering synthetic killer circuits in bacteria Proceedings of the 44th annual Design Automation Conference

F Reza, K Chandran, M Feltz, A Heinz, E Josephs, P O'Brien, B Van Dyke, H Chung, S Indurkhya, N Lakhani, J Lee, S Lin, N Tang, T LaBean, L You, F Yuan, J Tian Engineering novel synthetic biological systems IET Synthetic Biology

2006

H Song, C Tan, L You Living computers MOLECULAR BIOSYSTEMS

C Tan, H Song, J Niemi, L You A synthetic biology challenge: making cells compute Mol. BioSyst.

L You, D Tu, J Lee, T Ozdere, T Jun Lee Engineering Gene Circuits Nanotechnology in Biology and Medicine: Methods, Devices, and Applications

C Tan, H Song, J Niemi, L You Molecular BioSystems Mol. BioSyst

T Lee, C Tan, D Tu, L You Modeling cellular networks Bioinformatics: An Engineering Case-Based Approach

D Tu, J Lee, T Ozdere, T Lee, L You Engineering gene circuits: foundations and applications. Nanotechnology in biology and medicine: methods, devices, and applications.

H Song, L You Evolving sensitivity ACS Chemical Biology

L You, J Yin Evolutionary design on a budget: robustness and optimality of bacteriophage T7 Systems biology

2005

FK Balagaddé, L You, CL Hansen, FH Arnold, SR Quake Long-term monitoring of bacteria undergoing programmed population control in a microchemostat Science

FK Balagadde, L You, FH Arnold, SR Quake Programmed population control by cell-cell communication in microfluidic chemostats Biophysical Journal

2004

L You, RS Cox, R Weiss, FH Arnold Programmed population control by cell–cell communication and regulated killing Nature

L You Toward computational systems biology Cell biochemistry and biophysics

L You, A Hoonlor, J Yin Modeling biological systems using Dynetica—a simulator of dynamic networks Bioinformatics

R Srivastava, L You, J Summers, J Yin Stochastic vs. deterministic modeling of intracellular viral kinetics Journal of Theoretical Biology

Earlier publications

L You, PF Suthers, J Yin Effects of Escherichia coli physiology on growth of phage T7 in vivo and in silico Journal of bacteriology

L You, J Yin Dependence of epistasis on environment and mutation severity as revealed by in silico mutagenesis of phage T7 Genetics

L You, J Yin Simulating the growth of viruses Proc. Pac. Symp. Biocomput

L You, J Yin Patterns of regulation from mRNA and protein time series Metabolic engineering

D Endy, L You, J Yin, IJ Molineux Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes Proceedings of the National Academy of Sciences

L YOU, J YIN Amplification and spread of viruses in a growing plaque Journal of theoretical biology

L You, Q Liu, Y Shi, CX Wang, M Lahaye, V Tran The conformational study of β-D-GlcA-(1, 4)-L-Rha in solution by NMR and molecular dynamics simulations Chemical physics